{"id":4634,"date":"2012-11-05T06:31:27","date_gmt":"2012-11-04T22:31:27","guid":{"rendered":"https:\/\/2blog.ilc.edu.tw\/1909\/2012\/11\/05\/%e6%96%b0%e8%81%9e%e4%b8%ad%e7%9a%84%e7%a7%91%e5%ad%b8%ef%bd%9e%e7%a0%b4%e8%a7%a3%e7%b4%b0%e8%83%9e%e5%88%ba%e6%bf%80%e5%8f%8d%e6%87%89%e9%97%9c%e9%8d%b5\/"},"modified":"2021-03-18T19:44:04","modified_gmt":"2021-03-18T11:44:04","slug":"%e6%96%b0%e8%81%9e%e4%b8%ad%e7%9a%84%e7%a7%91%e5%ad%b8%ef%bd%9e%e7%a0%b4%e8%a7%a3%e7%b4%b0%e8%83%9e%e5%88%ba%e6%bf%80%e5%8f%8d%e6%87%89%e9%97%9c%e9%8d%b5","status":"publish","type":"post","link":"https:\/\/2blog.ilc.edu.tw\/1909\/2012\/11\/05\/%e6%96%b0%e8%81%9e%e4%b8%ad%e7%9a%84%e7%a7%91%e5%ad%b8%ef%bd%9e%e7%a0%b4%e8%a7%a3%e7%b4%b0%e8%83%9e%e5%88%ba%e6%bf%80%e5%8f%8d%e6%87%89%e9%97%9c%e9%8d%b5\/","title":{"rendered":"\u65b0\u805e\u4e2d\u7684\u79d1\u5b78\uff5e\u7834\u89e3\u7d30\u80de\u523a\u6fc0\u53cd\u61c9\u95dc\u9375"},"content":{"rendered":"

 <\/p>\n

\u00a0\u00a0 \u570b\u4e2d\u5b78\u751f\u5c0d\u65bc[\u7cd6\u5c3f\u75c5\u60a3\u8005\u70ba\u4f55\u6703\u6709\u7cd6\u5c3f\u75c5?<\/span><\/span>]\u7684\u8a8d\u77e5\u901a\u5e38\u662f:<\/span><\/span><\/span><\/p>\n

\u00a0 \u56e0\u70ba\u60a3\u8005\u7121\u6cd5\u5206\u6ccc\u80f0\u5cf6\u7d20\uff0c\u56e0\u6b64\u7121\u6cd5\u6709\u6548\u964d\u4f4e\u8840\u7cd6\u6fc3\u5ea6<\/span>\u3002<\/span><\/span><\/span><\/p>\n

\u5728\u95b1\u8b80\u5b8c\u9019\u7bc7\u4e4b\u5f8c\uff0c\u81ea\u7136\u6559\u5e2b\u53ef\u4ee5\u8a66\u8457\u7528\u66f4\u5c08\u696d\u3001\u66f4\u65b0\u7684\u7814\u7a76\u6210\u679c\u4f86\u89e3\u91cb\uff1a<\/span><\/p>\n

(1)\u300e\u7cd6\u5c3f\u75c5\u60a3\u8005\u662f\u56e0\u70ba\u7d30\u80de\u611f\u61c9\u5668\uff08\u53c8\u7a31\u53d7\u9ad4\uff09\uff0c\u6c92\u6709\u63a5\u53d7\u5230\u8cc0\u723e\u8499\u6216\u8840\u7cd6\u6fc3\u5ea6\u7570\u5e38\u7684\u8a0a\u00a0\u00a0 \u865f\uff0c\u6240\u4ee5\u6c92\u6709\u5206\u6ccc\u80f0\u5cf6\u7d20\uff0c\u56e0\u6b64\u7121\u6cd5\u964d\u4f4e\u8840\u7cd6\u6fc3\u5ea6\u3002\u300f<\/span><\/p>\n

(2)\u751a\u81f3\u53ef\u4ee5\u8b93\u5b78\u751f\u53bb\u89e3\u91cb\u770b\u770b\u70ba\u4f55\u6709\u4e9b\u4eba\u7684\u9ad4\u8cea\u6703\u5c0d\u5496\u5561\u56e0\u6709\u8f03\u660e\u986f\u7684\u53cd\u61c9\uff0c<\/span><\/p>\n

\u00a0\u00a0 \u4f8b\u5982\uff1a\u5fc3\u60b8\u3001\u96e3\u4ee5\u5165\u7720\u3002<\/span><\/p>\n

\u00a0\u00a0 \u4e5f\u662f\u56e0\u70ba\u4e0d\u540c\u9ad4\u8cea\u7684\u4eba\uff0c\u6709\u4eba\u53ef\u4ee5\u6709\u548c\u5496\u5561\u56e0\u7d50\u5408\u7684\u86cb\u767d\uff0c\u4e00\u65e6\u6b64\u86cb\u767d\u8207\u5496\u5561\u56e0\u7d50\u5408\uff0c<\/span><\/p>\n

\u00a0\u00a0 \u5c31\u6703\u5728\u6bd4\u8f03\u77ed\u6642\u9593\u5c07\u5496\u5561\u56e0\u4ee3\u8b1d\u51fa\u53bb\uff0c\u6240\u4ee5\u4e0d\u6703\u7522\u751f\u5fc3\u60b8\u3001\u96e3\u4ee5\u5165\u7720\u7684\u8208\u596e\u72c0\u614b\u3002<\/span><\/p>\n

\u00a0\u00a0 \u5982\u679c\u8eab\u9ad4\u5167\u6c92\u6709\u53ef\u4ee5\u548c\u5496\u5561\u56e0\u7d50\u5408\u7684\u86cb\u767d\uff0c\u5247\u5496\u5561\u56e0\u6703\u505c\u7559\u5728\u8eab\u9ad4\u5167\u8f03\u4e45\u7684\u6642\u9593\uff0c<\/span><\/p>\n

\u00a0\u00a0\u00a0 \u56e0\u6b64\u4eba\u4e5f\u6703\u6bd4\u8f03\u9577\u6642\u9593\u8d95\u5230\u6709\u96e3\u4ee5\u5165\u7720\u7684\u8208\u596e\u72c0\u614b\u3002<\/span><\/p>\n

(3)\u7626\u8089\u7cbe\uff08\u840a\u514b\u591a\u5df4\u80faRactopamine\uff09\u5c31\u662f\u8c9d\u4ed6-\u814e\u4e0a\u817a\u53d7\u9ad4\u6fc0\u52d5\u5291\u7684\u5176\u4e2d\u4e00\u7a2e\u3002<\/span><\/p>\n

\u00a0\u00a0\u00a0 \u5728\u52d5\u7269\u9ad4\u5167\u6703\u5f71\u97ff\u9aa8\u9abc\u808c\u3001\u8102\u80aa\u7d44\u7e54\u7684\u751f\u9577\u548c\u4ee3\u8b1d\uff0c\u53ef\u4ee5\u589e\u9032\u7626\u8089\u6bd4\u7387\u3002<\/span><\/p>\n

\u00a0\u00a0\u00a0\u00a0 \u5584\u7528\u7684\u8a71\uff0c\u53ef\u4ee5\u6cbb\u7642\u4eba\u9ad4\u7684\u547c\u5438\u9053\u75be\u75c5\u5982\u54ee\u5598\u3001\u652f\u6c23\u7ba1\u708e\u3002<\/span><\/p>\n

\u00a0<\/span><\/p>\n

 <\/p>\n

\u632a\u5a01\u756b\u5bb6\u5b5f\u514b\uff08Edvard Munch\uff091893\u5e74\u7684\u4f5c\u54c1\u300c\u5436\u558a\u300d\uff08\u5728\u8afe\u8c9d\u723e\u5316\u5b78\u5f97\u734e\u539f\u7406\u5716\u4e2d\u7684\u5de6\u65b9\uff09\uff0c<\/span><\/span><\/p>\n

\u50cf\u662f\u63cf\u8ff0\u4e86\u4eca\u5e74\u8afe\u8c9d\u723e\u5316\u5b78\u734e\uff1a<\/span><\/p>\n

\u4f60\u662f\u591c\u6b78\u7684\u4eba\uff0c\u5f9e\u504f\u9060\u7684\u516c\u8eca\u7ad9\u8d70\u56de\u5bb6\u3002<\/span><\/p>\n

\u7a81\u7136\uff0c\u4f60\u807d\u5230\u80cc\u5f8c\u6709\u8173\u6b65\u8072\uff0c\u800c\u4e14\u8d8a\u4f86\u8d8a\u8fd1\u3002<\/span><\/p>\n

\u96d6\u7136\u4f60\u544a\u8a34\u81ea\u5df1\u4e0d\u8981\u5bb3\u6015\uff0c\u90a3\u53ea\u662f\u53e6\u4e00\u500b\u591c\u6b78\u4eba\u58eb\uff0c\u4f46\u662f\u5fc3\u88e1\u8d8a\u4f86\u8d8a\u6bdb\u2026\u2026<\/span><\/p>\n

\u4f60\u5fcd\u4e0d\u4f4f\u958b\u59cb\u62d4\u817f\u72c2\u5954\uff0c\u6253\u958b\u5bb6\u9580\u8dd1\u9032\u53bb\uff0c\u6e3e\u8eab\u767c\u6296\u3001\u5fc3\u8df3\u52a0\u901f\u3001\u731b\u5598\u5927\u6c23\u3002<\/span><\/p>\n

<\/p>\n

\u96f7\u592b\u79d1\u7dad\u8332\uff08\u5de6\uff09\u8207\u67ef\u7562\u723e\u5361\uff08\u53f3\uff09\u540c\u7372\u672c\u5c46\u8afe\u8c9d\u723e\u5316\u5b78\u734e\u3002 \uff08\u8def\u900f\uff09<\/p>\n

<\/p>\n

\u8afe\u8c9d\u723e\u5316\u5b78\u734e\u5f97\u4e3b\u67ef\u7562\u723e\u5361\uff08\u5de6\uff09\u7684\u59bb\u5b50\u7530\u6771\u5c71\u662f\u83ef\u88d4\uff0c\u4e5f\u5728\u4ed6\u7684\u5be6\u9a57\u5ba4\u4efb\u8077\uff0c\u662f\u6a19\u6e96\u7684\u8ce2\u5167\u52a9\u3002 \uff08\u8def\u900f\uff09<\/p>\n

\u70ba\u4ec0\u9ebc\u6703\u9019\u6a23\uff1f<\/span><\/p>\n

\u7f8e\u570b\u79d1\u5b78\u5bb6\u96f7\u592b\u79d1\u7dad\u8332\uff08Robert Lefkowitz\uff09\u3001\u67ef\u7562\u723e\u5361\uff08Brian Kobilka\uff09<\/span><\/p>\n

\u6df1\u5165\u7814\u7a76\u7d30\u80de\u5982\u4f55\u56de\u61c9\u5916\u4f86\u523a\u6fc0\uff0c\u8aaa\u660e\u53d7\u5230\u523a\u6fc0\u6642\uff0c\u4eba\u9ad4\u5982\u4f55\u53cd\u61c9\uff0c<\/span><\/p>\n

\u4e5f\u5c31\u662f\u544a\u8a34\u4f60\u70ba\u4ec0\u9ebc\u6703\u9019\u6a23\u3002\u4ed6\u5011\u5171\u540c\u7372\u5f97\u4eca\u5e74\u8afe\u8c9d\u723e\u5316\u5b78\u734e\u3002 <\/span><\/p>\n

\u4eba\u9ad4\u7684\u773c\u775b\u3001\u9f3b\u5b50\u3001\u5634\u5df4\u7b49\u5668\u5b98\u53ef\u4ee5\u611f\u53d7\u5916\u754c\u7684\u5149\u548c\u6c23\u5473\uff0c\u4eba\u9ad4\u5167\u7684\u7d30\u80de\u4e5f\u4e00\u6a23\uff1b<\/span><\/p>\n

\u4eba\u9ad4\u7d30\u80de\u5927\u591a\u6709\u7279\u5b9a\u529f\u80fd\uff0c\u4f8b\u5982\u8caf\u5b58\u8102\u80aa\u3001\u88fd\u9020\u8377\u723e\u8499\u7b49\u3002<\/span><\/p>\n

\u5982\u679c\u4eba\u9ad4\u8981\u767c\u63ee\u61c9\u6709\u7684\u529f\u80fd\uff0c\u7d30\u80de\u4e4b\u9593\u5fc5\u9808\u5408\u4f5c\u7121\u9593\uff0c<\/span><\/p>\n

\u611f\u53d7\u76ee\u524d\u7684\u74b0\u5883\uff0c<\/span>\u4e5f\u638c\u63e1\u5468\u570d\u7684\u52d5\u614b\uff1b<\/span><\/p>\n

\u6240\u4ee5\u7d30\u80de\u9700\u8981\u611f\u61c9\u5668\uff0c\u7d30\u80de\u8868\u9762\u7684\u611f\u61c9\u5668\u53c8\u7a31\u300c\u53d7\u9ad4\u300d\u3002 <\/span><\/p>\n

\u96f7\u592b\u79d1\u7dad\u8332\u8207\u67ef\u7562\u723e\u5361\u56e0\u70ba\u7814\u7a76\u300cG\u86cb\u767d\u8026\u5408\u53d7\u9ad4\u300d\uff08GPCRs\uff09\u4e2d\u7684\u300c\u03b2\uff0d\u814e\u4e0a\u817a\u7d20\u53d7\u9ad4\u300d\u7d50\u69cb\uff0c\u4ee5\u53ca\u5b83\u5011\u5728\u4eba\u9ad4\u5167\u7684\u904b\u4f5c\u6a5f\u5236\u800c\u7372\u734e\u3002 <\/span><\/p>\n

GPCRs\u662f\u4e00\u500b\u5f88\u5927\u7684\u300c\u5bb6\u65cf\u300d\uff0c\u4e2d\u592e\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb\u526f\u6559\u6388\u5b6b\u7dad\u6b23\u6307\u51fa\uff0c<\/span><\/p>\n

\u4ee5\u4eba\u9ad4\u70ba\u4f8b\uff0cGPCRs\u662f700\u591a\u7a2e\u53d7\u9ad4\u7684\u7d71\u7a31\uff0c\u5b83\u5011\u63a5\u53d7\u4e86\u5305\u62ec\u814e\u4e0a\u817a\u7d20\u3001\u591a\u5df4\u80fa<\/span>\u3001\u8840\u6e05\u7d20\u3001\u5149\u7dda\u3001\u53e3\u5473\u8207\u55c5\u89ba\u7b49\u53d7\u9ad4\u7269\u8cea\u3002<\/span><\/p>\n

\u8a31\u591a\u751f\u7406\u4f5c\u7528\u90fd\u8207GPCRs\u6709\u95dc\uff0c\u76ee\u524d\u4e5f\u5927\u7d04\u6709\u4e00\u534a\u7684\u85e5\u7269\u4f8b\u5982\u6297\u7d44\u7e54\u80fa\u3001\u7cbe\u795e\u75be\u75c5\u85e5\u7269\u7b49\u900f\u904eGPCRs\u53d7\u9ad4\u7269\u8cea\u767c\u63ee\u4f5c\u7528\u3002 <\/span><\/p>\n

GPCRs\u5e7e\u4e4e\u53c3\u8207\u4e86\u6bcf\u4e00\u9805\u751f\u7406\u529f\u80fd\uff0c\u7fa9\u5b88\u5927\u5b78\u91ab\u5b78\u9662\u526f\u9662\u9577\u9ec3\u58eb\u54f2\u89e3\u91cb\uff0c<\/span><\/p>\n

\u53d7\u9ad4\u86cb\u767d\u8cea\u5728\u7d30\u80de\u819c\u4e0a\uff0c<\/span><\/p>\n

\u5b83\u5075\u6e2c\u62b5\u9054\u7d30\u80de\u8868\u9762\u7684\u8cc0\u723e\u8499\u3001\u795e\u7d93\u50b3\u5c0e\u5316\u5b78\u7269\u8cea\u3001\u6c23\u5473\u8207\u5176\u4ed6\u8a0a\u606f\u5206\u5b50\uff0c<\/span><\/p>\n

\u7136\u5f8c\u6d3b\u5316\u7d30\u80de\u5167\u7684G\u86cb\u767d\uff0c\u9032\u800c\u8a98\u767c\u5f71\u97ff\u77e5\u89ba\u3001\u884c\u70ba\u3001\u53ca\u5fc3\u8df3\u901f\u7387\u548c\u8840\u58d3\u7b49\u57fa\u790e\u529f\u80fd\u3002<\/span><\/p>\n

\u9019\u4e9b\u8a0a\u606f\u50b3\u5c0e\u9014\u5f91\u82e5\u51fa\u73fe\u529f\u80fd\u7570\u5e38\uff0c\u5247\u6703\u5c0e\u81f4\u7cd6\u5c3f\u75c5\u3001<\/span>\u8996\u89ba\u969c\u7919\u3001\u6c23\u5598\u3001\u6182\u9b31\u75c7\u53ca\u764c\u75c7\u7b49\u75be\u75c5\u3002 <\/span><\/p>\n

<\/span><\/p>\n

\u79d1\u5b78\u5bb6\u5011\u572819\u4e16\u7d00\u672b\u5c31\u767c\u73fe\u814e\u4e0a\u817a\u7d20\u53ef\u4ee5\u8b93\u4eba\u9ad4\u7522\u751f\u5fc3\u8df3\u52a0\u901f\u3001\u8840\u58d3\u5347\u9ad8\u7b49\u5f71\u97ff\u3002<\/span><\/p>\n

\u4f46\u662f\uff0c\u7576\u6642\u7684\u79d1\u5b78\u5bb6\u9084\u4e0d\u4e86\u89e3\u7d30\u80de\u5167\u90e8\u5982\u4f55\u5f9e\u5916\u754c\u63a5\u6536\u8a0a\u865f\uff0c\u9032\u800c\u7522\u751f\u53cd\u61c9\u3002<\/span><\/p>\n

\u9019\u4e00\u5207\u7684\u7955\u8a23\u7531\u7f8e\u570b\u79d1\u5b78\u5bb6\u96f7\u592b\u79d1\u7dad\u8332\uff08Robert Lefkowitz\uff09\u3001\u67ef\u7562\u723e\u5361\uff08Brian Kobilka\uff09\u7814\u7a76\u300cG\u86cb\u767d\u8026\u5408\u53d7\u9ad4\u300d\uff08GPCRs\uff09\u4e2d\u7684\u300c\u03b2\uff0d\u814e\u4e0a\u817a\u7d20\u53d7\u9ad4\u300d\u7d50\u69cb\uff0c<\/span><\/p>\n

\u4ee5\u53ca\u5b83\u5011\u5728\u4eba\u9ad4\u5167\u7684\u904b\u4f5c\u6a5f\u5236\u800c\u89e3\u958b\u3002 <\/span><\/p>\n

\u96f7\u592b\u79d1\u7dad\u8332\u3001\u67ef\u7562\u723e\u5361\u5171\u540c\u7372\u5f97\u4eca\u5e74\u8afe\u8c9d\u723e\u5316\u5b78\u734e\u3002<\/span><\/p>\n

\u4e2d\u592e\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb\u526f\u6559\u6388\u5b6b\u7dad\u6b23\u6307\u51fa\uff0c\u03b2\uff0d\u814e\u4e0a\u817a\u7d20\u53d7\u9ad4\u7d50\u69cb\u662f\u79d1\u5b78\u5bb6\u5011\u7b2c2\u500b\u7834\u89e3\u7684GCPRs\u7d50\u69cb\uff0c\u76ee\u524d\u9084\u6c92\u6709\u7b2c3\u500b\u3002 <\/span><\/p>\n

\u5b6b\u7dad\u6b23\u8868\u793a\uff0cGPCRs\u548c\u4eba\u9ad4\u6578\u767e\u7a2e\u53d7\u9ad4\u6709\u95dc\u3002<\/span><\/p>\n

2000\u5e74\u5de6\u53f3\uff0c\u79d1\u5b78\u5bb6\u89e3\u958bGPCRs\u5bb6\u65cf\u4e2d\u7b2c1\u500b\u53d7\u9ad4\uff1b\u5b83\u53eb\u300c\u8996\u7d2b\u7d05\u8cea\u53d7\u9ad4\u300d\uff08rhodopsin receptor\uff09\uff0c\u5b58\u5728\u65bc\u8996\u7db2\u819c\u687f\u72c0\u7d30\u80de\uff0c\u662f\u4e00\u7a2e\u5448\u73ab\u7470\u7d05\u8272\u7684\u8996\u7db2\u819c\u8272\u7d20\uff0c\u5b83\u53ef\u4ee5\u8b93\u8996\u7db2\u819c\u8b8a\u8272\uff0c\u4e5f\u662f\u52d5\u7269\u611f\u77e5\u5149\u7dda\u7684\u6700\u4e3b\u8981\u7269\u8cea\u3002 <\/span><\/p>\n

\u5b6b\u7dad\u6b23\u8aaa\uff0c\u03b2\uff0d\u814e\u4e0a\u817a\u7d20\u53d7\u9ad4\u662fGPCRs\u5bb6\u65cf\u4e2d\uff0c\u7b2c2\u500b\u88ab\u7834\u89e3\u7684\u86cb\u767d\u8cea\u7d50\u69cb\u3002<\/span><\/p>\n

\u96f7\u592b\u79d1\u7dad\u8332\u662f\u7b2c1\u500b\u767c\u73fe\u3001\u4e26\u8a73\u7d30\u7814\u7a76\u03b2\uff0d\u814e\u4e0a\u817a\u7d20\u53d7\u9ad4\u5728\u4eba\u9ad4\u5167\u50b3\u905e\u8a0a\u606f\u7684\u6a5f\u5236\uff0c\u4e5f\u627e\u5230\u4e86\u4e00\u4e9b\u8abf\u6574\u3001\u63a7\u5236\u4eba\u9ad4\u53cd\u61c9\u7684\u86cb\u767d\u8cea\u3002\u03b2\uff0d\u814e\u4e0a\u817a\u7d20\u53d7\u9ad4\u7684\u7d50\u69cb\u5247\u7531\u96f7\u592b\u79d1\u7dad\u8332\u3001\u67ef\u7562\u723e\u5361\u4ee5X\u5149\u7d50\u6676\u5b78\u65b9\u6cd5\u5408\u4f5c\u89e3\u51fa\u3002<\/span> <\/span><\/p>\n

\u7fa9\u5b88\u5927\u5b78\u91ab\u5b78\u9662\u526f\u9662\u9577\u9ec3\u58eb\u54f2\u89e3\u91cb\uff0c\u53d7\u9ad4\u86cb\u767d\u8cea\u5728\u7d30\u80de\u819c\u4e0a\uff0c\u5b83\u63a5\u6536\u5916\u754c\u8a0a\u865f\u5f8c\uff0c\u50b3\u5230\u7d30\u80de\u88e1\u7684G\u86cb\u767d\uff0c\u518d\u5f15\u767c\u7d30\u80de\u53cd\u61c9\u3002\u03b2\uff0d\u814e\u4e0a\u817a\u7d20\u53d7\u9ad4\u53ef\u4ee5\u63a5\u53d7\u814e\u4e0a\u817a\u7d20\u548c\u6b63\u814e\u4e0a\u817a\u7d20\u7b49\uff0c\u5728\u67d0\u4e9b\u60c5\u6cc1\u4e0b\u63a7\u5236\u4eba\u9ad4\u5fc3\u8df3\u5feb\u6162\u3001\u8178\u80c3\u8815\u52d5\u3001\u61c9\u4ed8\u7dca\u6025\u72c0\u6cc1\u7b49\u3002 <\/span><\/p>\n

\u5b6b\u7dad\u6b23\u6307\u51fa\uff0c\u9019\u4e9b\u548c\u4eba\u9ad4\u5167\u7684\u795e\u7d93\u50b3\u5c0e\u3001\u8377\u723e\u8499\u90fd\u6709\u95dc\uff0c\u53ef\u4ee5\u5f15\u767c\u300c\u751f\u75c5\u300d\u53cd\u61c9\uff0c<\/span><\/p>\n

\u4e86\u89e3\u4e86\u5b83\u7684\u6a5f\u5236\u548c\u7d50\u69cb\uff0c\u624d\u80fd\u300c\u5c0d\u75c7\u4e0b\u85e5\u300d\uff0c<\/span>\u6216\u76f4\u6307\u75c7\u72c0\u958b\u767c\u85e5\u7269\u3002<\/span><\/p>\n

 <\/p>\n

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\u76ee\u524d\u4e16\u754c\u4e0a\u5927\u7d0450\uff05\u7684\u85e5\u7269\u90fd\u56e0\u70ba\u9019\u9805\u7814\u7a76\u624d\u5f97\u4ee5\u958b\u767c\uff0c\u570b\u5167\u76f8\u95dc\u7684\u7814\u7a76\uff0c\u4e5f\u4ee5\u85e5\u7406\u548c\u751f\u7406\u5b78\u9818\u57df\u5b78\u8005\u53c3\u8207\u6700\u591a\u3002 <\/span><\/p>\n

\u9ec3\u58eb\u54f2\u89e3\u91cb\uff0c\u4eba\u9ad4\u7d30\u80de\u6709\u7d30\u80de\u819c\u8207\u5916\u754c\u9694\u7d55\uff0c\u7d30\u80de\u819c\u5916\u7684\u8a0a\u606f\u4e3b\u8981\u9760GPCRs\u63a5\u6536\u3001\u50b3\u905e\u5230\u7d30\u80de\u819c\u5167\uff0c\u9032\u800c\u5f15\u767c\u7d30\u80de\u5167\u5668\u5b98\u751a\u81f3\u662f\u8eab\u9ad4\u795e\u7d93\u3001\u817a\u9ad4\u505a\u51fa\u53cd\u61c9\u3002 <\/span><\/p>\n

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\u4eca\u5e74\u7684\u8afe\u8c9d\u723e\u734e\u8a55\u5be9\u5728\u516c\u5e03\u7684\u6587\u4ef6\u63d0\u5230\uff0c\u79d1\u5b78\u5bb6\u5011\u8981\u4e86\u89e3\u300c\u53d7\u9ad4\u300d\uff0c\u624d\u80fd\u7814\u767c\u526f\u4f5c\u7528\u8f03\u5c11\u7684\u66f4\u597d\u85e5\u7269\u3002 <\/span><\/p>\n

\u7f8e\u570b\u79d1\u5b78\u5bb6\u96f7\u592b\u79d1\u7dad\u8332\uff08Robert Lefkowitz\uff09\u3001\u67ef\u7562\u723e\u5361\uff08Brian Kobilka\uff09\u56e0\u70ba\u7814\u7a76GPCRs\u4e2d\u7684\u300c\u03b2\uff0d\u814e\u4e0a\u817a\u7d20\u53d7\u9ad4\u300d\u7d50\u69cb\u800c\u7372\u734e\u3002\u5176\u5be6\uff0c\u524d\u4e00\u9663\u5b50\u5728\u53f0\u7063\u793e\u6703\u5f15\u767c\u4e0d\u5c0f\u722d\u8b70\u7684\u300c\u7626\u8089\u7cbe\u300d\u4e5f\u8207\u6b64\u6709\u95dc\u3002 <\/span><\/p>\n

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  \u00a0\u00a0 \u570b\u4e2d\u5b78\u751f\u5c0d\u65bc[\u7cd6\u5c3f\u75c5\u60a3\u8005\u70ba\u4f55\u6703\u6709\u7cd6\u5c3f\u75c5?]\u7684\u8a8d\u77e5...<\/p>\n","protected":false},"author":297,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[],"class_list":["post-4634","post","type-post","status-publish","format-standard","hentry","category-c-64234"],"meta_key":{"lt_post_id":["335050"],"_pingme":["1"],"_encloseme":["1"]},"_links":{"self":[{"href":"https:\/\/2blog.ilc.edu.tw\/1909\/wp-json\/wp\/v2\/posts\/4634"}],"collection":[{"href":"https:\/\/2blog.ilc.edu.tw\/1909\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/2blog.ilc.edu.tw\/1909\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/2blog.ilc.edu.tw\/1909\/wp-json\/wp\/v2\/users\/297"}],"replies":[{"embeddable":true,"href":"https:\/\/2blog.ilc.edu.tw\/1909\/wp-json\/wp\/v2\/comments?post=4634"}],"version-history":[{"count":1,"href":"https:\/\/2blog.ilc.edu.tw\/1909\/wp-json\/wp\/v2\/posts\/4634\/revisions"}],"predecessor-version":[{"id":5031,"href":"https:\/\/2blog.ilc.edu.tw\/1909\/wp-json\/wp\/v2\/posts\/4634\/revisions\/5031"}],"wp:attachment":[{"href":"https:\/\/2blog.ilc.edu.tw\/1909\/wp-json\/wp\/v2\/media?parent=4634"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/2blog.ilc.edu.tw\/1909\/wp-json\/wp\/v2\/categories?post=4634"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/2blog.ilc.edu.tw\/1909\/wp-json\/wp\/v2\/tags?post=4634"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}